Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history
We are seeking a research associate in the ADPE group (12-month contract). The candidate is expected to support the Protein Sciences team in providing high-quality biologics in a timely manner for biochemical, biophysical, and biological characterizations to drive the advancement of novel therapeutics. The candidate will be responsible for the purification, QC of all biologic molecules ( including bispecific and multi-specific antibodies, fusion proteins) and will support developability studies. Tasks will include analytics of proteins by analytical SEC, SDS-PAGE, DSF, DLS, endotoxin assessment, etc. Purification strategies will include the use of AKTA systems and various chromatography techniques (protein-A/G, Ni-NTA, SEC, IEX, HIC, etc).
Responsibilities:

• Responsible for purification of high-quality monoclonal antibodies, bi-specific/multi-specific antibodies, fusion proteins, as well as reagent proteins from CHO cells and HEK293 cells
• Early molecular assessment for antibody developability evaluation
• Document and present experimental results at team meetings

Qualifications:

• B.S. with 0-2 years of industry experience
• Self-motivated and highly collaborative with excellent oral and written communication skills and organization skills
• Strong desire to drive technical innovation
• Experience with protein purification and a wide range of biochemical/biophysical and analytical methods, such as SDS-PAGE, HPLC/UHPLC, DSF, DLS, endotoxin quantitation/removal
• Ability to thrive in a fast-paced environment in a creative, open, collaborative, team-oriented setting

$25 - $35 an hour
Hourly rate ranges will be determined by the candidate's level, qualifications, skill set, and experience.
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At Alector, our vision is bold, people are our priority, and our values are at the core of everything we do. Our dynamic and flexible environment encourages our teams to experiment, take ownership of decisions, and question convention to solve complex problems. We value shared wins, perseverance, and a growth mindset, which drives us forward, together.
Among the things you'll discover at Alector from your very first day are our committed and driven colleagues, a bold company vision, and new, modern offices designed to inspire innovation and collaboration in South San Francisco, right at the heart of Biotech Bay. Our benefits are thoughtfully designed around Alectorians and their loved ones and include flexible hybrid work options, competitive compensation, and comprehensive and unique benefits that enhance your health and well-being. Come join us!
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